{"id":1917,"date":"2023-02-24T15:28:01","date_gmt":"2023-02-24T06:28:01","guid":{"rendered":"https:\/\/www.gotoku.co.jp\/wordpress\/?page_id=1917"},"modified":"2025-05-28T14:23:25","modified_gmt":"2025-05-28T05:23:25","slug":"ns300","status":"publish","type":"page","link":"https:\/\/www.gotoku.co.jp\/en\/ns300\/","title":{"rendered":"NS-300\u00ae"},"content":{"rendered":"\n

\"\" NS-300\u00ae<\/sup><\/h2>\n\n\n
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Product Info<\/div>\n\t\t\t<\/div>
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Reference Data<\/div>\n\t\t\t<\/div><\/div>\n\t\t\t<\/div>\n\t\t\t
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What is NS-300\u00ae<\/sup><\/span><\/strong><\/p>\n\n\n\n

NS-300\u00ae<\/sup> (carmellose) is a cellulose-based disintegrant with excellent wicking properties.
NS-300\u00ae<\/sup><\/span> acts as a passageway for water and has the effect of allowing water to quickly permeate the inside of the formulation.
No organic solvents are used in the manufacturing process, so there is no need to worry about residual solvents.<\/span><\/p>\n\n\n\n

Basic Information<\/span><\/strong><\/p>\n\n\n\n

Product name: NS-300\u00ae<\/sup><\/span>
Generic name: Carmellose
Packing style: 20kg slotted cardboard box (2-layer polyethylene inner bag)
Quality-assurance standards\uff1a Japanese Pharmacopoeia
\u3000\u3000\u3000\u3000Three(3) Pharmacopoeias\uff08JP\u30fbUSP-NF\u30fbEP\uff09are available.
DMF Registration Number: US Registration No. 19767
\u3000\u3000\u3000\u3000\u3000\u3000\u3000 China Registration No. F20180001743<\/span><\/p>\n\n\n\n

Acceptance Criteria<\/strong><\/span><\/strong><\/p>\n\n\n\n

Parameters JP<\/th>Specifications JP<\/th>Ref. USP-NF<\/th>Ref. EP<\/th>Our test Method<\/th><\/tr><\/thead>
Description<\/strong><\/td><\/td><\/td><\/td><\/td><\/tr>
\u3000Appearance<\/td>a white powder<\/td>Meets specification<\/td>JP test method<\/td>Ditto<\/td><\/tr>
Identification<\/strong><\/td><\/td><\/td><\/td><\/td><\/tr>
\u3000(1) Infrared absorption<\/td>compare the spectrum with the Reference Spectrum: both spectra exhibit similar intensities of absorption at the same wave numbers<\/td>Meets specification<\/td>Meets specification<\/td>Ditto<\/td><\/tr>
\u3000(2) pH (1% suspension)<\/td>between 3.5 and 5.0<\/td>3.5 - 5.0<\/td>33.5 - 5.0<\/td>Ditto<\/td><\/tr>
Purity<\/strong><\/td><\/td><\/td><\/td><\/td><\/tr>
\u3000(1)\u00a0 Chlorides<\/td>not more than 0.36 %<\/td>\u22660.36%<\/td>\u22660.36%<\/td>Ditto<\/td><\/tr>
\u3000(2)\u00a0 Sulfates<\/td>not more than 0.72 %<\/td>\u22660.72%<\/td>\u22660.72%<\/td>Ditto<\/td><\/tr>
Loss on drying<\/strong><\/td>not more than 8.0 %<\/td>\u22668.0%<\/td>\u22668.0%<\/td>Ditto<\/td><\/tr>
Residue on ignition<\/strong><\/td>not more than 1.5 %<\/td>\u22661.5%<\/td>\u22661.5%<\/td>Ditto<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

<\/p>\n\n\n\n

Rational and Molecular formula<\/span><\/strong>
Rational formula\uff1a
\uff3bC6<\/sub>H7<\/sub>O2<\/sub>(OH)3-X<\/sub> (OCH2<\/sub>COOH)X<\/sub>\uff3dn<\/strong><\/p>\n\n\n\n

<\/p>\n\n\n\n

\"\"<\/figure>\n\n<\/div>
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Average Particle Size\u30fbPowder Properties<\/span><\/strong><\/p>\n\n\n\n

Product Name<\/strong><\/td>Average Particle Size\u203b1<\/sup><\/strong><\/td>Powder Properties\u203b2<\/sup><\/strong><\/td><\/tr>
D10<\/sub>
\uff08\u03bcm\uff09<\/td>		D50<\/sub>
\uff08\u03bcm\uff09<\/td>		D90<\/sub>
\uff08\u03bcm\uff09<\/td>		Loose Bulk Density
\uff08g\/L\uff09<\/td>		Tap Density
\uff08g\/L\uff09<\/td>		Angle of Repose
\uff08degree\uff09<\/td><\/tr>
NS-300<\/strong>\u00ae<\/strong><\/sup><\/span><\/td>22<\/td>54<\/td>134<\/td>387<\/td>561<\/td>45<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n

\u203b1\u3000Reference value (laser diffraction type)
\u203b2\u3000Reference value<\/span><\/p>\n\n\n\n

SEM Image<\/strong><\/span><\/p>\n\n\n\n

\"\"<\/figure>\n\n<\/div><\/div>\n\t\t<\/div>\n\n\n

<\/p>\n","protected":false},"excerpt":{"rendered":"

NS-300\u00ae<\/p>\n","protected":false},"author":5,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_editorskit_title_hidden":false,"_editorskit_reading_time":1,"_editorskit_is_block_options_detached":false,"_editorskit_block_options_position":"{}","_monsterinsights_skip_tracking":false,"_locale":"en_US","_original_post":"https:\/\/www.gotoku.co.jp\/wordpress\/?page_id=1826","sns_share_botton_hide":"","vkExUnit_sns_title":"","_vk_print_noindex":"","sitemap_hide":"","vkExUnit_sitemap":"","_veu_custom_css":"h2 img {\r\n vertical-align: middle;\r\n}","veu_display_promotion_alert":"common","_exclude_from_list_pages":"","vkexunit_cta_each_option":"","vkExUnit_childPageIndex":"","vkExUnit_pageList_ancestor":"","vkExUnit_contact_enable":"","_lightning_design_setting":{"layout":"default"},"footnotes":""},"class_list":["post-1917","page","type-page","status-publish","hentry","en-US"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t