History
| 1949 | Shoichi Nakayama (Founder) established Gotoku Chemical Promotion Partnership Corporation for the purpose of the distribution of chemicals,food additives and the like. | |
| 1950 | Launched CMC-Na (Carboxymethyl cellulose Sodium, also known as Cellulose Glycolate) under the trade name of T.P.T-㋩® (Trademark creator, Shoichi Nakayama), based on the license of the Agency of Industrial Science and Technology (of those days). | |
| 1961 | Playing a central role, Gotoku Chemical researched and developed Disintegrant, CMC-Ca (Official name for the food additive = Calcium Cellulose Glycolate) to be successful in commercialization. Brought it to market under the trade name of E.C.G-505® (Trade name creator, Shoichi Nakayama) and launched market cultivation as the exclusive distributor to extend sales activities nationwide. | |
| 1963 | CMC-Ca (Calcium Cellulose Glycolate) was listed in the Japan's Specifications and Standards for Food Additives (The 4th edition) and approved as a food additive. Launched E.C.G-FA® as a food additive. (Gotoku Chemical = Exclusive distributor) | |
| 1966 | E.C.G-505® (JP official name, Carmellose Calcium) was listed in the Japanese Pharmacopoeia (JP) 7th edition (the second part). Approved as one of JP drugs. | |
| 1967 | Originally researched and developed Disintegrant, CMC-H (Acid-type carboxymethylcellulose) to accomplish commercialization. Brought it to market under the trade name of NS-300® (Trade name creator, Shoichi Nakayama). Advanced market cultivation as the exclusive distributor of NS-300® with the goal of nationwide sales. | |
| 1985 | Founder, Shoichi Nakayama acceded to Representative Partner & Chairman. Yukihiro Nakayama was designated as Representative Partner & President (after Accounting Manager, Sales Manager and Vice-President). E.C.G-505® was listed in USP-NF, having a high international valuation. | |
| 1986 | NS-300® (JP official name = Carmellose) was listed in the Japanese Pharmacopoeia (11th edition). Approved as one of JP drugs. | |
| 1989 | At the time of the 40th anniversary of the foundation, Partnership was reorganized into Company Limited. Gotoku Chemical Co.,Ltd. newly started. Yukihiro Nakayama acceded to Representative Director & President. | |
| 1991 | E.C.G-505® was elected to one of the pharmaceutical excipients of Japan. U.S.A and Europe, "ICH Harmonization Monographs" (25 items used very often in the world). | |
| 1993 | The performance of E.C.G-505® was recognized in Europe and E.C.G-505® was listed in European Pharmacopoeia (EP). | |
| 1996 | Highly evaluated abroad, NS-300® was listed in "the Addendum of ICH Harmonization monographs". | |
| 2006 | NS-300® was registered in DMF (Drug Master File). *Registration No.19767 | |
| 2010 | Highly evaluated across the world, NS-300® was listed in USP-NF and EP. | |
| 2015 | The performance of E.C.G-505® was approved and listed in ChP. | |
| 2016 | E.C.G-505® was registered in DMF (Drug Master File). *Registration No.030379 | |
| 2019 | E.C.G-505® was registered in Chinese DMF (Drug Master File) | *Registration No.F20180001742 |
| NS-300® was registered in Chinese DMF (Drug Master File) | *Registration No.F20180001743 | |
| Opened a liaison office in London / the United Kingdom. | ||
| Note: USP=United States Pharmacopoeia, NF=National Formulary, EP=European Pharmacopoeia ChP=Chinese Pharmacopoeia | ||
